Cholesterol Disorders

Cholesterol disorders, particularly high levels of LDL (bad cholesterol), can lead to plaque buildup in arteries, increasing the risk of heart disease. Contributing factors include diet, weight, and genetics.

Symptoms

• Generally asymptomatic
• High cholesterol can lead to atherosclerosis (hardening of arteries) and cardiovascular disease

Complications

• Heart attack
• Stroke
• Peripheral artery disease

Medications

1. Statins: Lower LDL cholesterol and stabilize existing plaque.
2. Fibrates: Reduce triglycerides and increase HDL (good cholesterol).
3. PCSK9 Inhibitors: A newer class of medications that significantly lower LDL cholesterol.

Lifestyle Considerations

• Maintain a diet low in saturated and trans fats
• Engage in regular exercise
• Avoid tobacco products

Managing cholesterol levels effectively involves a combination of medication and lifestyle changes to reduce the risk of serious cardiovascular complications.