Sofradex Cream (15g) is a combination medication containing three active ingredients: dexamethasone (a corticosteroid), framycetin (an antibiotic), and gramicidin (an antibiotic). It is used to treat inflammatory skin conditions that are also complicated by bacterial infections, such as dermatitis, eczema, and infected wounds. Dexamethasone reduces inflammation, while framycetin and gramicidin work to kill bacteria.